COMBAT Shiny Apps

Bulk RNA-seq principal component analysis
PCA has been performed on the full data set, the reduced data set (one priority sample per individual) and the hospitalised COVID samples. This Shiny app allows you to select PCs to plot, and explore their relationship with different clinical covariates.

Bulk RNA-seq differential expression analysis
Differential expression analysis has been performed using limma on the full and the reduced data sets (one priority sample per individual), accounting for a choice of key covariates. This Shiny app presents differences between each comparator group with volcano plots and summary tables. The expression of specific genes can also be visualised as boxplots across the comparator groups.